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Tetrahedron letters

Molecular iodine-catalyzed one-pot synthesis of substituted quinolines from imines and aldehydes

XF Lin, SL Cui, YG Wang

文献索引:Lin, Xu-Feng; Cui, Sun-Liang; Wang, Yan-Guang Tetrahedron Letters, 2006 , vol. 47, # 18 p. 3127 - 3130

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被引用次数: 97

摘要

Quinoline and their derivatives, which usually possess diverse biological activities, play important roles as versatile building blocks for the synthesis of natural products and as therapeutic agents. 1 In particular, 2-arylquinolines are biologically active and occur in structures of a number of antimalarial compounds and antitumor agents. 2 Therefore, the synthesis of quinolines has attracted much attention in organic synthesis. The classic methods for the synthesis of ...