Acylthioureas as anion transporters: the effect of intramolecular hydrogen bonding

…, J Herniman, ME Light, NJ Wells, I Marques…

文献索引：Haynes, Cally J. E.; Busschaert, Nathalie; Kirby, Isabelle L.; Herniman, Julie; Light, Mark E.; Wells, Neil J.; Marques, Igor; Felix, Vitor; Gale, Philip A. Organic and Biomolecular Chemistry, 2014 , vol. 12, # 1 p. 62 - 72

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被引用次数: 38

摘要

Small molecule synthetic anion transporters may have potential application as therapeutic agents for the treatment of diseases including cystic fibrosis and cancer. Understanding the factors that can dictate the anion transport activity of such transporters is a crucial step towards their application in biological systems. In this study a series of acylthiourea anion transporters were synthesised and their anion binding and transport properties in POPC ...