Tetrahedron

Methodology for the synthesis of 1, 2-disubstituted arylnaphthalenes from α-tetralones

SS Moleele, JP Michael, CB de Koning

文献索引：Moleele, Simon S.; Michael, Joseph P.; De Koning, Charles B. Tetrahedron, 2006 , vol. 62, # 12 p. 2831 - 2844

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被引用次数: 33

摘要

α-Tetralones were initially converted into 1-bromo-dihydronaphthalene-2-carbaldehydes and 1-bromo-naphthalene-2-carbaldehydes. These precursors were then subjected to Suzuki coupling reactions to afford 1, 2-disubstituted aryldihydronaphthalenes and 1, 2- disubstituted arylnaphthalenes, respectively. The former products were oxidized with DDQ to give 1, 2-disubstituted arylnaphthalenes.