Nickel??Catalyzed Coupling of Thiomethyl??Substituted 1, 3??Benzothiazoles with Secondary Alkyl Grignard Reagents

A Ghaderi, T Iwasaki, A Fukuoka…

文献索引：Ghaderi, Arash; Iwasaki, Takanori; Fukuoka, Asuka; Terao, Jun; Kambe, Nobuaki Chemistry - A European Journal, 2013 , vol. 19, # 9 p. 2951 - 2955

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被引用次数: 10

摘要

Transition-metal catalyzed CÀC bond-forming reaction is a useful and straightforward method for the functionalization of azole heterocycles,[1] which are frequently found as key frameworks in natural products, pharmaceutics, and organic functional materials.[2a] Because the C2 position of 1, 3-azoles, such as oxazoles, thiazoles, and imidazoles, in many natural and synthetic compounds are alkylated,[2b–g] the development of simple ...