Cyanosilylation of aldehydes and ketones catalyzed by nanocrystalline magnesium oxide

…, K Mahendar, B Sreedhar, K Vijay Kumar…

文献索引：Lakshmi Kantam; Mahendar, Koosam; Sreedhar, Bojja; Vijay Kumar; Choudary Synthetic Communications, 2008 , vol. 38, # 22 p. 3919 - 3936

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被引用次数: 11

摘要

Abstract Cyanosilylation of various aldehydes and ketones with TMSCN proceeded smoothly under mild conditions to give the corresponding cyanohydrin trimethylsilyl ethers in the presence of nanocrystalline magnesium oxide. The cyanohydrin trimethylsilyl ethers of aldehydes produced cyanohydrins in good to high yields on treatment with 2 N HCl. 29Si NMR spectral evidence proved that the reaction proceeds through the hypervalent silicate ...