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α-Oxygenated Pyridines. IV. The Synthesis of an Isomer of Pyridoxamine1, 2

RP Mariella, EP Belcher

文献索引:Mariella; Belcher Journal of the American Chemical Society, 1952 , vol. 74, p. 4049

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被引用次数: 4

摘要

Methyl Methoxyacetate. Method A.-A solution of 374 g. of chloroacetic acid in 200 ml. of methanol containing 50 ml. of concentrated sulfuric acid was refluxed for six hours. The solution was neutralized with a saturated solution of sodium bicarbonate, filtered, and the aqueous layer ex-tracted with ether. The dried ether extract was distilled. The methyl chloroacetate boiled at 126-130', 304.8 g.(717, yield).