Synthesis of 4??hydrazino??5H??pyrimido [5, 4??b] indole and related compounds

A Monge, JA Palop, T Goni…

文献索引：Monge; Palop; Goni; et al. Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 647 - 649

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被引用次数: 8

摘要

Abstract This paper describes the synthesis of two 4-amino-5H-pyrimido [5, 4-b] indoles 5, 4- hydrazino-5H-pyrimido [5, 4-b] indole 6, two 1, 2, 4-triazolo [4, 3-c] pyrimido [5, 4-b] indoles 8, and tetrazolo [4, 5-c] pyrimido [5, 4-b] indole 10. Starting with ethyl 3-aminoindole-2- carboxylate 1, 5H-pyrimido [5, 4-b] indol-4-one 2 was obtained (80%) by condensing with formamide. Reactions of 2 with phosphorus oxychloride and phosphorus pentasulfide ...