Dalton Transactions

A facile access to a novel bidentate enantiomerically pure P, N-donor ligand

CK Seubert, Y Sun, WR Thiel

文献索引：Seubert, Christoph K.; Sun, Yu; Thiel, Werner R. Dalton Transactions, 2009 , # 25 p. 4971 - 4977

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被引用次数: 6

摘要

As outlined in Schemes 1 and 2, the synthesis of the target ligand follows a convergent strategy with an overall yield of about 70%. Although the precursor compound 2 has already been described in the literature, 14 we decided to develop an alternative access, since it was only obtained along with its regioisomer 5-(2-hydroxyphenyl)(1-methyl)pyrazole. The separation of the two isomers requires column chromatography. A few years ago, we reported the synthesis of ...