Regioselective and efficient synthesis of N 7-substituted adenines, guanines, and 6-mercaptopurines

M Maryška, N Chudíková, V Kotek, D Dvořák…

文献索引：Maryska, Michal; Chudikova, Nadezda; Kotek, Vladislav; Dvorak, Dalimil; Tobrman, Tomas Monatshefte fur Chemie, 2013 , vol. 144, # 4 p. 501 - 507

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被引用次数: 3

摘要

Abstract A simple and efficient protocol for the preparation of N 7-substituted adenines, guanines, and 6-mercaptopurines is described. The key step is the regioselective preparation of 7-substituted 6-chloropurines which are building blocks for the divergent synthesis of adenines, guanines, and 6-mercaptopurines by known procedures. Graphical abstract