Tetrahedron Letters

Ruthenium-catalyzed direct amination of alcohols with tertiary amines

J Luo, M Wu, F Xiao, G Deng

文献索引：Luo, Jiaying; Wu, Mingyue; Xiao, Fuhong; Deng, Guojun Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2706 - 2709

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被引用次数: 15

摘要

Abstract A highly selective phosphine-based ruthenium catalyst system efficiently catalyzes the direct amination of alcohols with aliphatic tertiary amines, yielding unsymmetric tertiary amines in yields up to 87%. Ligand and solvent both affect the reaction yields significantly. The reaction can be performed with a wide variety of functionalities.