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The synthesis of Fmoc-O-allyl β-serine

…, S Jalal, HR Lagiakos, MI Aguilar, P Perlmutter

文献索引:Bergman, Ylva; Ciampini, Marisa; Jalal, Sania; Lagiakos, Helen Rachel; Aguilar, Marie-Isabel; Perlmutter, Patrick Tetrahedron Asymmetry, 2008 , vol. 19, # 24 p. 2861 - 2863

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被引用次数: 5

摘要

Two concise routes for the synthesis of the title amino acid have been developed. The first route employs Seebach's general approach [Seebach, D.; Lelais, G.; Micuch, P.; Josien- Lefebvre, D.; Rossi, F. Helv. Chim. Acta2004, 87, 3131] with Arndt Eistert homologation of Boc-O-allyl α-serine as the key process. The second route employs an approach using Boc- α-aspartic acid as a starting material [Salzmann, TN; Ratcliffe, RW; Christensen, BG; ...