Letters in Organic Chemistry

Stereoselective chlorination of new type Baylis-Hillman adducts by bis (trichloromethyl) carbonate with the aid of catalytic amount of triphenylphosphine oxide

W Zhong, L Hong, Y Zheng

文献索引：Zhong, Weihui; Hong, Lingjuan; Zheng, Yemin Letters in Organic Chemistry, 2010 , vol. 7, # 3 p. 229 - 234

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被引用次数: 2

摘要

INTRODUCTION Baylis-Hillman adducts have been successfully utilized as valuable intermediates for stereoselective synthesis of different multifunctional molecules [1,2]. In particular, the halogenation of Baylis-Hillman adducts has attracted much attention in recent years [3,4], since they can be employed for the synthesis of various natural bioactive products and their analogues, such as micanecic acid, kizanolide, rennin inhibitor A-72517, β-lactams, α-methylene-γ- ...