Reactions of [1, 2, 3] triazolo [1, 5-c] pyrimidine 2 with some electrophiles and nucleophiles are reported. Triazole ring opening and loss of nitrogen is the principal reaction with electrophiles. With strong acids protonation on N6 competes successfully. Derivatives in which the pyrimidine ring has been opened are obtained in reactions with nucleophiles. No stable simple substitution compounds were found.
![[1,2,3]-triazolo[1,5-c]pyrimidine结构式](https://image.chemsrc.com/caspic/364/49689-16-9.png)
