Synthesis of functionalized 3-chloro-1-naphthols via Friedel–Crafts acylation of vinyl chlorides

…, M McLaughlin, C Chen, RA Reamer, L Dimichele…

文献索引：Linghu, Xin; McLaughlin, Mark; Chen, Cheng-Yi; Reamer, Robert A.; Dimichele, Lisa; Davies, Ian W. Tetrahedron Letters, 2012 , vol. 53, # 13 p. 1550 - 1552

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被引用次数: 1

摘要

Friedel–Crafts type cyclization of vinyl chlorides was developed into a general method for the synthesis of functionalized naphthols. The chloro functional group contained within these products allowed for further elaboration via cross-coupling reactions, leading to increased structural complexity.