Tetrahedron Letters

Total synthesis of amorfrutin A via a palladium-catalyzed migratory prenylation–aromatization sequence

S Laclef, K Anderson, AJP White, AGM Barrett

文献索引：Laclef, Sylvain; Anderson, Katie; White, Andrew J.P.; Barrett, Anthony G.M. Tetrahedron Letters, 2012 , vol. 53, # 2 p. 225 - 227

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被引用次数: 12

摘要

The total synthesis of amorfrutin A, a prenyl bibenzyl natural product has been achieved in five steps from 2, 2, 6-trimethyl-4H-1, 3-dioxin-4-one. The key step of the synthesis is an efficient palladium (0)-catalyzed decarboxylative prenylation migration and aromatization sequence.