Shuttle–Cargo Fusion Molecules of Transport Peptides and the hD2/3 Receptor Antagonist Fallypride: A Feasible Approach To Preserve Ligand–Receptor Binding?

…, G Fricker, KT Wanner, R Schirrmacher

文献索引：Iovkova-Berends, Ljuba; Waengler, Carmen; Zoeller, Thomas; Hoefner, Georg; Wanner, Klaus Theodor; Rensch, Christian; Bartenstein, Peter; Kostikov, Alexey; Schirrmacher, Ralf; Jurkschat, Klaus; Waengler, Bjoern Molecules, 2011 , vol. 16, # 9 p. 7458 - 7479

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被引用次数: 1

摘要

To determine if the conjugation of a small receptor ligand to a peptidic carrier to potentially facilitate transport across the blood–brain barrier (BBB) by “molecular Trojan horse” transcytosis is feasible, we synthesized several transport peptide–fallypride fusion