Reactions of cysteine sulfenyl thiocyanate with thiols to give unsymmetrical disulfides

SL Alguindigue Nimmo, K Lemma…

文献索引：Alguindigue Nimmo, Susan L.; Lemma, Kelemu; Ashby, Michael T. Heteroatom Chemistry, 2007 , vol. 18, # 5 p. 467 - 471

全文：HTML全文

被引用次数: 14

摘要

Abstract Cysteine sulfenyl thiocyanate (CSSCN) reacts with thiols at pH 0 to cleanly yield disulfides. 2-Mercaptoethanol (2-MESH), 3-mercaptopropionic acid (3-MPASH), penicillamine (PENSH), and glutathione (GSH) react with CSSCN to give the corresponding mixed disulfides: 2-MESSC, 3-MPASSC, PENSSC, and GSSC. These compounds are stable at pH 0 and have been characterized by 1 H and 13 C NMR spectroscopy.© 2007 Wiley ...