Anilinoquinazoline inhibitors of fructose 1, 6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography

SW Wright, AA Carlo, MD Carty…

文献索引：Journal of Medicinal Chemistry, , vol. 45, # 18 p. 3865 - 3877

被引用次数: 84

摘要

... Journal of Medicinal Chemistry. ... Cambridge, Massachusetts 02139. J. Med. Chem. , 2002, 45 (18), pp 3865–3877. DOI: 10.1021/jm010496a. Publication Date (Web): July 26, 2002. Copyright © 2002 American Chemical Society. ...

75332-44-4

3,4-二乙氧基苯甲酸乙酯

179246-15-2

6,7-二乙氧基喹唑啉-4(3H)-酮

~83%

Anilinoquinazoline inhibitors of fructose 1, 6-bisphosphatas...

[Wright, Stephen W.; Carlo, Anthony A.; Carty, Maynard D.; Danley, Dennis E.; Hageman, David L.; Karam, George A.; Levy, Carolyn B.; Mansour, Mahmoud N.; Mathiowetz, Alan M.; McClure, Lester D.; Nestor, Nestor B.; McPherson, R. Kirk; Pandit, Jayvardhan; Pustilnik, Leslie R.; Schulte, Gayle K.; Soeller, Walter C.; Treadway, Judith L.; Wan, Ing-Kae; Bauer, Paul H. Journal of Medicinal Chemistry, 2002 , vol. 45, # 18 p. 3865 - 3877]

Anilinodialkoxyquinazolines: screening epidermal growth fact...

[Journal of Medicinal Chemistry, , vol. 48, # 23 p. 7445 - 7456]