Tetrahedron letters

One-step preparation of 1-substituted tetrahydroisoquinolines via the Pictet–Spengler reaction using zeolite catalysts

A Hegedüs, Z Hell

文献索引：Hegedues, Adrienn; Hell, Zoltan Tetrahedron Letters, 2004 , vol. 45, # 46 p. 8553 - 8555

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被引用次数: 44

摘要

A new, environmentally friendly variation of the Pictet–Spengler reaction has been elaborated using a small pore size zeolite. The easily separable and recyclable catalyst provided high conversions and a shorter reaction time than the classical acetic acid or trifluoroacetic acid.