Abstract Emissive RNA homonucleosides were added to the growing library of synthetic probes. The emissive nucleobases were constructed in one step from the methallyl C- glycoside of D-ribofuranose, which was prepared stereoselectively. The homonucleosides displayed various emission colors by using a single excitation wavelength that could be fine- tuned merely by changing the carbonyl substituent on the methoxyphenol.
