Tetrahedron

Halogen atom transfer radical cyclization of N-allyl-N-benzyl-2, 2-dihaloamides to 2-pyrrolidinones, promoted by Fe 0-FeCl 3 or CuCl-TMEDA

M Benedetti, L Forti, F Ghelfi, UM Pagnoni, R Ronzoni

文献索引：Benedetti, Miriam; Forti, Luca; Ghelfi, Franco; Pagnoni, Ugo Maria; Ronzoni, Roberto Tetrahedron, 1997 , vol. 53, # 41 p. 14031 - 14042

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被引用次数: 65

摘要

The halogen atom transfer radical cyclization of a N-allyl-N-benzyl-2, 2-dihaloamides to 2- pyrrolidinones has been carried out in high yields under mild conditions, in a reaction promoted by CuCl-TMEDA or Fe0-FeCl3 in acetonitrile or N, N-dimethylformamide, respectively.