Journal of Fluorine Chemistry

Synthesis and anti-microbial activity of some new fluorinated 1H-pyrazoles

DJ Wang, L Fan, CY Zheng, ZD Fang

文献索引：Wang, Dun-Jia; Fan, Ling; Zheng, Chun-Yang; Fang, Zheng-Dong Journal of Fluorine Chemistry, 2010 , vol. 131, # 5 p. 584 - 586

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被引用次数: 32

摘要

Several new trifluoromethyl-1H-pyrazoles were prepared by reaction of hydrazine monohydrate with 1, 3-diketones. Their structures were confirmed by elemental analysis, IR, 1H NMR and EI-MS spectroscopy. The anti-microbial activities of the newly synthesized compounds were examined by disc diffusion method against Escherichia coli, Staphylococcus aureus, Pyricularia oryzae and Rhizoctnia solani. All the trifluoromethyl- ...