Amino Acids

2-Oxo-2H-benzo [h] benzopyran as a new light sensitive protecting group for neurotransmitter amino acids

AMS Soares, SPG Costa, MST Gonçalves

文献索引：Soares, Ana M. S.; Costa, Susana P. G.; Goncalves, M. Sameiro T. Amino Acids, 2010 , vol. 39, # 1 p. 121 - 133

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被引用次数: 24

摘要

Abstract Aiming at the development of new benzopyran-based photocleavable protecting groups, novel chloromethylated and hydroxymethylated 2-oxo-2 H-benzo [h] benzopyran derivatives bearing a methoxy substituent were designed and used in the synthesis of a series of fluorescent bioconjugates, by linking through an ester or urethane bond to several model neurotransmitter amino acids (glycine, alanine, β-alanine and γ-aminobutyric acid, ...