Synthesis, rapid resolution, and determination of absolute configuration of racemic 2, 2'-binaphthyldiyl crown ethers and analogs via. beta.-cyclodextrin complexation

…, TJ Ward, A Czech, BP Czech, RA Bartsch

文献索引：Armstrong, Daniel W.; Ward, Timothy J.; Czech, Anna; Czech, Bronislaw P.; Bartsch, Richard A. Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5556 - 5559

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被引用次数: 64

摘要

Twenty racemic and four diastereomeric 2, 2'-binaphthyldiyl crown ethers and analogues were synthesized. Chiral interactions between these compounds and immobilized P- cyclodextrin were examined. Thirteen of the enantiomeric pairs and two of the diastereomers were successfully resolved. It was found that relatively small changes in the structure of these compounds could have large effects on chiral recognition. In general, the (-)-S ...