Tetrahedron

Synthesis of polyanionic glycopolymers for the facile assembly of glycosyl arrays

…, H Ito, M Izumi, H Tokuhisa, K Taguchi, N Minoura

文献索引：Uzawa, Hirotaka; Ito, Hiroki; Izumi, Masayuki; Tokuhisa, Hideo; Taguchi, Kazuhiro; Minoura, Norihiko Tetrahedron, 2005 , vol. 61, # 24 p. 5895 - 5905

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被引用次数: 31

摘要

Polyanionic glycopolymers were synthesized aiming at establishing a simple process for assembling glycosyl arrays. The synthetic glycopolymers carry the key carbohydrate epitopes of α-d-galactobioside (Gb2), β-lactoside, and α-d-mannopyranoside, each of which serves as a ligand of bacterial toxins and adhesion proteins. The Gb2 epitope, prepared from penta-O-acetyl-d-galactopyranose, was coupled with poly (ethylene-alt-maleic ...