Chemical Communications

Selective cleavage of ketals and acetals under neutral, anhydrous conditions using triphenylphosphine and carbon tetrabromide

C Johnstone, WJ Kerr, JS Scott

文献索引：Johnstone, Craig; Kerr, William J.; Scott, James S. Chemical Communications, 1996 , # 3 p. 341 - 342

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被引用次数: 46

摘要

The deprotection of ketals and acetals, in particular the 1,3-dioxolanes, to the corresponding carbonyl compound is a transformation of considerable importance in organic synthesis. Regeneration of the aldehyde or ketone is normally accom- plished by aqueous acid hydrolysis.' In the case of compounds possessing acid-sensitive functionality, a number of alternative methods, some of which use non-aqueous conditions, have been developed. These include the use of ...