Syntheses of new chiral bicyclic sultams and their use as auxiliaries in asymmetric conjugate addition of Grignard reagents

U Chiacchio, A Corsaro, G Gambera, A Rescifina…

文献索引：Chiacchio, Ugo; Corsaro, Antonino; Gambera, Giovanni; Rescifina, Antonio; Piperno, Anna; Romeo, Roberto; Romeo, Giovanni Tetrahedron Asymmetry, 2002 , vol. 13, # 17 p. 1915 - 1921

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被引用次数: 19

摘要

Minor variations in the structure of an auxiliary may exert great influence on the effectiveness of the asymmetric induction in a chemical transformation. 5 Although natural products are convenient sources of chiral auxiliaries, their effectiveness is relatively difficult to optimize via systematic structural modifications. In contrast, chiral auxiliaries based on rational chemical design provide greater flexibility for improvement through structural variations. ... Recently, 6., and we ...