Efficient asymmetric synthesis of ABT-594; a potent, orally effective analgesic

JK Lynch, MW Holladay, KB Ryther, H Bai…

文献索引：Tetrahedron Asymmetry, , vol. 9, # 16 p. 2791 - 2794

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被引用次数: 38

摘要

... Tetrahedron: Asymmetry. Volume 9, Issue 16, 21 August 1998, Pages 2791–2794. ... 3. Treatment of 2-chloro-5-aminopyridine 5 with boron trifluoride etherate and t-butylnitrite generated the diazonium salt which was decomposed in acetic anhydride [9]to give 2-chloro-5 ...