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Structure-Activity Relationship of Quinoline Derivatives as Potent and Selective α2C-Adrenoceptor Antagonists

IPJ Höglund, S Silver, MT Engström…

文献索引:Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6351 - 6363

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被引用次数: 30

摘要

... Journal of Medicinal Chemistry. ... compounds and aspects of their structure−activity relationship on human α 2C -adrenoceptors. Chemistry. The quinoline derivatives 5 and 6 in the present study were prepared via a ...