Polycyclic N??hetero compounds. XXIX. Synthesis and antidepressive evaluation of 15??thia??11, 13??diazasteroidal analogues and their precursors

T Hirota, R Hamazaki, T Ohdoi…

文献索引：Hirota; Hamazaki; Ohdoi; et al. Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 341 - 344

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被引用次数: 6

摘要

Abstract Syntheses of novel 15-thia-11, 13-diazasteroidal skeleton IV and its D-homo analogues are described. Meso-ionic derivatives of IV were also synthesized. Antidepressive activities of these compounds and their precursors were screened. D- Dihomothiadiazasteroid IX and 3, 4, 5, 6-tetrahydrobenzo [h] quinazoline-4-thione (V) exhibited antireserpine action.