Tetrahedron letters

Enantioselective introduction of a benzenesulfonylmethyl substituent at an unactivated carbon atom via chemoenzymatic methods

AR Maguire, LL Kelleher

文献索引：Maguire, Anita R.; Kelleher, Leonard L. Tetrahedron Letters, 1997 , vol. 38, # 42 p. 7459 - 7462

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被引用次数: 13

摘要

Introduction of a benzenesulfonylmethyl group at the unactivated γ-carbon of carboxylic acid derivatives has been achieved through a combination of rhodium acetate catalysed carbenoid C H insertion and baker's yeast mediated kinetic resolution. Access to the two complementary enantiomeric series of 6 with excellent enantiocontrol is possible.