Stereoselective synthesis of (+)-SCH 351448: A unique ligand system for sodium, calcium, and other cations

…, JS Kim, HJ Kim, SG Lee, MS Lah, E Lee

文献索引：Kang, Eun Joo; Cho, Eun Jin; Ji, Mi Kyung; Lee, Young Eun; Shin, Dong Mok; Choi, Soo Young; Chung, Young Keun; Kim, Jong-Seo; Kim, Hie-Joon; Lee, Sueg-Geun; Lah, Myoung Soo; Lee, Eun Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6321 - 6329

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被引用次数: 42

摘要

(+)-SCH 351448 (Na+ salt A) was synthesized employing ring-closing olefin metathesis reaction of an open diene diester intermediate for construction of the 28-membered macrodiolide structure. The open diene diester was prepared from the monomeric hydroxy carboxylic acid and two different olefin fragments. The monomeric hydroxy acid was synthesized via Julia-Julia coupling reaction of intermediates derived from the same ...