Process improvements in the synthesis of corticosteroid 9, 11β-epoxides

X Fu, CH Tann, TK Thiruvengadam

文献索引：Organic Process Research and Development, , vol. 5, # 4 p. 376 - 382

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被引用次数: 6

摘要

... Organic Process Research & Development. ... give rise to an impurity such as 11 via 19 at a level that is not purgable by the existing purification procedure. ... has been developed for the synthesis of β-epoxide 3 based on systematic studies of the deficiencies of the existing process. ...