Synthesis and biological activity of acridinyl-9-thioacetic acids and their derivatives

…, GP Kazakov, AA Kravchenko, LA Porokhnyak…

文献索引：Gaydukevich, A. N.; Kazakov, G. P.; Kravchenko, A. A.; Porokhnyak, L. A.; Pinchuk, V. V.; Velikii, D. L. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 9 p. 633 - 636 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 9 p. 1067 - 1070

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被引用次数: 2

摘要

Upon the action of NaOH the compounds IIa-g, like 9-thioacridone, are converted to the tautomer (thioi) derivatives, ie, the corresponding 6-chloro-9-thioacridines, which react readily with monoiodoacetic acid to form 6-chloroacridinyl-9-thioacetic acid (IIIa) and its derivatives (IIIb-g).