Design, construction and properties of peptide N-terminal cap templates devised to initiate α-helices. Part 1. Caps derived from N-(4-chlorobutyryl)-(2 S)-Pro-(2 S)-Pro- …

A Lewis, MD Ryan, D Gani

文献索引：Lewis, Arwel; Ryan, Martin D.; Gani, David Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 22 p. 3767 - 3775

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摘要

The structural features required of-terminal helix caps which might display high α-helix- forming propensities (Zimm–Bragg-values close to unity) were considered and two systems were identified as initial candidates for synthesis and evaluation. The first system was an eleven-membered cyclic all-triamide derived