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Synthesis and antiviral activity of various 3'-azido analogs of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV)

…, JY Guo, RF Schinazi, CK Chu, JN Xiang…

文献索引:Lin, Tai-Shun; Guo, Ji-Yu; Schinazi, Raymond F.; Chu, Chung K.; Xiang, Jia-Ning; Prusoff, Willian H. Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 336 - 340

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被引用次数: 122

摘要

28 cure, its ability to prolong life of AIDS patients, in spite of bone marrow suppression observed in some patients, has encouraged the evaluation of other AZT, as well as several other nucleoside analogues that are inhibitory to HIV-1 in vitro, was finst synthesized by Honvitz et al. 143