New COX-2/5-LOX inhibitors: apoptosis-inducing agents potentially useful in prostate cancer chemotherapy

N Pommery, T Taverne, A Telliez…

文献索引：Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6195 - 6206

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被引用次数: 117

摘要

... Journal of Medicinal Chemistry. ... Results and Discussion. Chemistry. Arylhydrazines 1b−j were commercially available, whereas methanesulfonylhydrazine 1a was obtained (Scheme 1) by nucleophilic substitution of 4-chlorophenylmethyl sulfone with hydrazine. ...