Intramolecular 1, 3??Dipolar Cycloaddition??Mediated Stereoselective Synthesis of Disubstituted Cyclopentane: A Simple Model for the Cyclopentane Ring System of …
Y Fukahori, Y Takayama, T Imaoka…
文献索引：Fukahori, Yusuke; Takayama, Yohei; Imaoka, Takuya; Iwamoto, Osamu; Nagasawa, Kazuo Chemistry - An Asian Journal, 2013 , vol. 8, # 1 p. 244 - 250
Abstract We present a diastereoselective synthesis of disubstituted cyclopentane 8 having a nitrogen-containing quaternary carbon center, which is found in axinellamine A (5) and related compounds. During this work, we found that the 1, 3-dipolar cycloaddition product 24 immediately underwent intramolecular redox reaction at the newly formed morpholin-2-one moiety, thus affording disubstituted cyclopentane containing a tertiary amine (9) ...
