Setting the record straight: The origin of the pharmacophore concept

OF Güner, JP Bowen

文献索引：Long; Schueler Journal of the American Pharmaceutical Association (1912-1977), 1954 , vol. 43, p. 79,80

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被引用次数: 13

摘要

... Journal of Chemical ... research points to Paul Ehrlich's 1898 paper for originating the concept, which identifies peripheral chemical groups in molecules responsible for binding that leads to the subsequent biological effect, and to Schueler's 1960 book ... “It has long been believed ...