Tetrahedron letters

A simple and efficient synthesis of 2,-3-, or 4-(2-nitrophenyl) pyridine derivatives via palladium catalyzed ullmann cross-coupling reaction

N Shimizu, T Kitamura, K Watanabe, T Yamaguchi…

文献索引：Shimizu, Noboru; Kitamura, Takahiro; Watanabe, Koichiro; Yamaguchi, Takashi; Shigyo, Hiromichi; Ohta, Tomio Tetrahedron Letters, 1993 , vol. 34, # 21 p. 3421 - 3424

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被引用次数: 33

摘要

The typical experiment was done as follows. A mixture of equimolar amounts of 1b, 3d and P(PPh 3 ) 4 in dimethylsulfoxide-d6 was heated at 100°C for 40 minutes. After the reaction was completed, the product ratio of iodo(3-pyridyl)bis(triphenylphosphine)palladium(II) (7) 8,9 to bromo(4-ethoxy-2-nitrophenyl)bis(triphenylphosphine)-palladium(II) (8) 10 was to be about 20 : 1 by the use of the integration values for the aromatic protons at δ 6.05 ppm (signal ...