The participation of lawsone (2-hydroxy-1, 4-naphthoquinone) in the Mannich reaction to give bases of type (I, R'= H) has already been reported by Leffler and Hathaway.'These authors found that the reaction proceeded readily using formaldehyde with, as the basic component, either primary aliphatic amines of relatively low molecular weight, or certain secondary amines such as dimethylamine, piperidine, morpholine, and various ...
![3-[(dodecylamino)methyl]-4-hydroxy-naphthalene-1,2-dione结构式](https://image.chemsrc.com/caspic/150/74227-89-7.png)