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Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein

F Manna, F Chimenti, R Fioravanti, A Bolasco…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 20 p. 4632 - 4635

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被引用次数: 135

摘要

... Bioorganic & Medicinal Chemistry Letters. ... designing new, potent selective, and less toxic anticancer agents is still a major challenge to medicinal chemistry researchers. ... The chemical and physical data are reported in Table 1. The microanalyses of derivatives 2a–u are reported ...