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Potential antiinflammatory agents. Aralkoxyhydrouracils and aralkoxyhydantoins

L Simet, DB Reisner, BJ Ludwig…

文献索引:Simet,L. et al. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 1067 - 1071

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被引用次数: 2

摘要

(4) See 1). J. Brown," The Pyrimidines," Interscience, New York, SP, 1962, pp 434-436, for a discussion. boxylation, or bj. reduction of an enamine of a P-lieto ester. Holyever, when R1 is aralkoxy, we found that only benzyloxyamine and a fen ring-substituted benzyloxyamines could be added to ethyl acrylate and these amines failed to add to methyl methacrylate. The aminomethylation reaction and enamine reduction also failed to yield the esters needed ...