Nucleotides. Part XXVIII. Chemical syntheses of the 2′??5′??cordycepin??trimer core

R Charubala, E Uhlmann, F Himmelsbach…

文献索引：Charubala; Uhlmann; Himmelsbach; Pfleiderer Helvetica Chimica Acta, 1987 , vol. 70, # 8 p. 2028 - 2038

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被引用次数: 19

摘要

Abstract The chemical synthesis of 3′-deoxyadenyly-(2′-5′)-3′-deoxyadenylyl-(2′- 5′)-3′-deoxyadenosine (30; trimeric cordycepin) is described by three different routes using various protecting groups and applying the phosphotriester approach. The intermediates have been isolated and characterized by elemental analyses and spectroscopic means. High yields of 30 have been obtained on deprotection making this ...