Tetrahedron Letters

An easy route for the synthesis of pyrazine-2, 3-dicarbonitrile 5, 6-bis-substituted derivatives using a palladium catalyst

H Ali, JE van Lier

文献索引：Ali, Hasrat; Van Lier, Johan E. Tetrahedron Letters, 2012 , vol. 53, # 36 p. 4824 - 4827

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被引用次数: 12

摘要

An easy synthetic method for the preparation of pyrazine-2, 3-dicarbonitrile 5, 6-bis- substituted derivatives using Pd-catalyzed cross coupling reaction (Sonogashira, Suzuki, Heck) is described. The reaction conditions allow preparing symmetrical and unsymmetrical