Synthesis and microbiological evaluation of several benzocaine derivatives

…, I Zarafu, MT Caproiu, C Draghici, M Maganu…

文献索引：Paun, Anca; Zarafu, Irina; Caproiu, Miron T.; Draghici, Constantin; Maganu, Maria; Cotar, Ani I.; Chifiriuc, Mariana C.; Ionita, Petre Comptes Rendus Chimie, 2013 , vol. 16, # 7 p. 665 - 671

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摘要

Abstract Starting from benzocaine, a well-known anaesthetic, ten derivatives were synthesized and characterized by UV–vis, IR, NMR, and elemental analysis. Most of the compounds contain residues with recognized biological activity, like nicotinic acid (vitamin B3 or PP), biotin (vitamin B7 or H), lipoic acid (thioctic acid), adamantine, as well as other residues of crown-ether type, benzofurazane, naphtylurea, di-and tri-nitrobenzene, and a ...