Synthesis

The Modified Julia Olefination in Vitamin D2 Synthesis

PR Blakemore, PJ Kocienski, S Marzcak, J Wicha

文献索引：Blakemore; Kocienski; Marzcak; Wicha Synthesis, 1999 , # 7 p. 1209 - 1215

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被引用次数: 27

摘要

Abstract: A partial synthesis of vitamin D2 employing fragments derived from a new improved degradation procedure is described. The 7, 8-double bond of the vitamin D triene system was synthesised via the modified Julia olefination. The new procedure is more efficient than the classical Julia olefination. Key words: vitamin D, alkene synthesis, sulfone, benzothiazole, one-pot Julia olefination