The samarium Grignard reaction. In situ formation and reactions of primary and secondary alkylsamarium (III) reagents

DP Curran, MJ Totleben

文献索引：Curran, Dennis P.; Totleben, Michael J. Journal of the American Chemical Society, 1992 , vol. 114, # 15 p. 6050 - 6058

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被引用次数: 199

摘要

Abstract: This work shows that primary and secondary radicals are rapidly reduced in THF/HMPA to form primary-and secondary-alkylsamarium reagents. The primary-and secondary-radicals can be formed either by direct SmI, reduction of primary-and secondary- halides or by a previous rapid radical cyclization. The samarium reagents have moderate stability in solution, and they react with a variety of typical electrophiles, including ...