Heterocycles

Solvent-free synthesis of quinolone derivatives

P Cernuchova, G Vo-Thanh, V Milata, A Loupy

文献索引：Cernuchova, Petra; Vo-Thanh, Giang; Milata, Viktor; Loupy, Andre Heterocycles, 2004 , vol. 64, p. 177 - 191

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被引用次数: 29

摘要

Résumé/Abstract Quinolones can be prepared in a three step procedure from triethylorthoformate and activated methylene derivatives leading to alkoxymethylenemalonates followed by reaction with aromatic amines and finally a cyclization. All the reactions were carried out under solvent-free conditions possibly under microwave activation with benefits for the first step.