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Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors

MA Schiffler, S Antonysamy…

文献索引:Fajgelj, Simona; Stanovnik, Branko; Tisler, Miha Heterocycles, 1986 , vol. 24, # 2 p. 379 - 386

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被引用次数: 8

摘要

... Volume: Page ... Imidazophenanthrolines such as MF-63 (1),(20) aryl indoles such as 2,(21) and oxicams such as PF-9184 (3)(22) have ... inhibit mPGES-1. In addition, an mPGES-1 inhibitor known as GRC-27864 has entered clinical trials for inflammatory pain.(24). ...